Renal tubular acidosis with hyperchloremic acidosis: harmless with a sting?

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Renal tubular acidosis with hyperchloremic acidosis: harmless with a sting?

Brunner et al. [1] showed a higher than previously described prevalence of renal tubular acidosis (RTA) in critically ill patients with hyperchloremic metabolic acidosis (HMA). They elegantly demonstrated that this condition often remains unrecognized owing to the simultaneous presence of metabolic alkalosis, mainly attributed to low plasma albumin levels, and was not associated with increased ...

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  Introduction Renal tubular acidosis (RTA) is a non-uremic defects of urinary acidification. It is characterized by a normal anion gap hyperchloremic  metabolic acidosis; plasma potassium may be normal, low or high-depending on the type of RTA. These syndromes differ from uremic acidosis which is associated with a high anion gap, decreased glomerular filtration with enhanced proton secretion b...

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Renal tubular acidosis.

Renal tubular acidosis is a relatively uncommon clinical syndrome characterized by the inability of the kidney to adequately excrete hydrogen ions, retain adequate bicarbonate, or both. This syndrome can be categorized into 3 separate disorders, each with unique clinical characteristics. Although an uncommon finding, prompt and inexpensive tests can lead to early intervention and subsequently r...

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Muscle weakness is a common neurological symptom but is rarely due to hypokalaemia consequent on renal disease, as in the patients reported here. Two types of acidosis occur in renal disease. The more common and unfortunately incurable is that complicating chronic renal failure. Less common, but since it is treatable, more important, is renal tubular acidosis. That described by Lightwood (1935)...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2015

ISSN: 1364-8535

DOI: 10.1186/s13054-015-1038-y